Membrane Transport Mechanisms

Research Goal

Our research delves into the molecular mechanisms of solute transport across biological membranes, focusing on those involved in human diseases. We seek to identify the structural and functional determinants that govern solute movement via active transmembrane carriers. This knowledge will enhance our understanding of solute homeostasis and the pathologies associated with transport dysfunction. In a multidisciplinary environment, we employ biochemical and biophysical techniques to characterize membrane transporters at the molecular level. By integrating high-resolution cryo-electron microscopy (cryo-EM) with functional assays, we aim to elucidate the precise structural and mechanistic basis of solute transport.