Research Goal
Our research is focused on understanding protein translocation through membrane pores and on the biotechnological applications of such processes.
Publications
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The emerging landscape of single-molecule protein sequencing technologies.
Nat Methods 18, 604–617 (2021) doi: 10.1038/s41592-021-01143-1 -
Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks
Biosensors and Bioelectronics, 180, 2021,113108, (2021) doi: 10.1016/j.bios.2021.113108 -
Transmembrane protein rotaxanes reveal kinetic traps in the refolding of translocated substrates
D. Commun Biol. 2020 3(1):159. (2020) doi: 10.1038/s42003-020-0840-5. (2020) -
Free-energy landscapes of membrane co-translocational protein unfolding
Commun Biol. 3(1):160. (2020) doi: 10.1038/s42003-020-0841-4. (2020) -
DNA-binding miniproteins based on Zinc Fingers. Assessment of the interaction using nanopores
Chemical Science. 2018. doi: 10.1039/C7SC05441F (2018)