Theoretical / Protocell Biophysics

Publications

• Cross-feeding percolation phase transitions of intercellular metabolic networks

  Sci Adv. 2025 Sep 5;11(36):eadv8216. doi: 10.1126/sciadv.adv8216. Epub 2025 Sep 3. PMID: 40901938; PMCID: PMC12407054.

• Modelling the prebiotic origins of regulation and agency in evolving protocell ecologies

  Philos Trans R Soc Lond B Biol Sci. 2025 Oct 2;380(1936):20240287. doi: 10.1098/rstb.2024.0287. Epub 2025 Oct 2. PMID: 41035323; PMCID: PMC12489503.

• Metabolic coordination and phase transitions in spatially distributed multi-cellular systems

  Commun Phys 8, 205 (2025). https://doi.org/10.1038/s42005-025-02133-x

• On the Evolutionary Development of Biological Organization from Complex Prebiotic Chemistry

  Book Chapter. In: Mossio, M. (eds) Organization in Biology. History, Philosophy and Theory of the Life Sciences, vol 33. Springer, Cham. Doi: 10.1007/978-3-031-38968-9_9

• Emergence of collective self-oscillations in minimal lattice models with feedback

  Phys. Rev. E 108, 044204. Doi: 10.1103/PhysRevE.108.044204

• Collectively autocatalytic sets

  Cell Reports Physical Science. 2023. Volume 4, Issue 10. 101594. Doi:10.1016/j.xcrp.2023.101594.

• The protometabolic nature of prebiotic chemistry

  Review. Chem Soc Rev. (2023) Oct 30;52(21):7359-7388. doi: 10.1039/d3cs00594a.

• Collective catalysis under spatial constraints: Phase separation and size-scaling effects on mass action kinetics

  Phys. Rev. E 108, 044410. Doi: 10.1103/PhysRevE.108.044410

• Statistical mechanics of biomolecular condensates via cavity methods

  iScience, Volume 26, Issue 4, 2023, 106300, ISSN 2589-0042. doi.org/10.1016/j.isci.2023.106300.

• Statistical modeling of adaptive neural networks explains co-existence of avalanches and oscillations in resting human brain

  Nat Comput Sci (2023). doi.org/10.1038/s43588-023-00410-9

• Relationship between fitness and heterogeneity in exponentially growing microbial populations

  Biophysical Journal (2022), doi.org/10.1016/j.bpj.2022.04.012

• Probing Single-Cell Fermentation Fluxes and Exchange Networks via pH-Sensing Hybrid Nanofibers

  ACS Nano 2022, doi.org/10.1021/acsnano.2c06114

• Epidemic oscillations induced by social network control

  J. Stat. Mech. (2022) 013404, doi.org/10.1088/1742-5468/ac4804

• Minimal metabolism: a key concept to investigate the origins and nature of biological systems.

  BioEssays, 43, e2100103, (2021) doi: 10.1002/bies.202100103

• Definitions of life as epistemic tools that reflect and foster the advance of biological knowledge

  Synthese. (2020) doi: 10.1007/s11229-020-02736-7. (2020)

• Boundary versus enabling conditions for the origins of life: Comment on \

  Phys Life Rev. 34-35:96-98. (2020) doi: 10.1016/j.plrev.2020.06.001 (2020)

• The Construction of Biological ‘Inter-Identity’ as the Outcome of a Complex Process of Protocell Development in Prebiotic Evolution

  Front Physiol. 11:530 (2020). doi: 10.3389/fphys.2020.00530 (2020)

• Oscillations in feedback-driven systems: Thermodynamics and noise

  PHYSICAL REVIEW E 100 (6), 062123 (2019) doi: 10.1103/PhysRevE.100.062123. (2019)

• Feedback-induced self-oscillations in large interacting systems subjected to phase transitions

  Journal of Physics A: Mathematical and Theoretical, 52(4), 045002 (2019) DOI: 10.1088/1751-8121/aaf2dd

• A plea for hypothesis-driven research in prebiotic systems chemistry

  Chem 5 (8), 1920-1922 (2019)

• Statistical mechanics for metabolic networks during steady state growth

  Nature communications, 9(1), 1-9 (2018) DOI: 10.1038/s41467-018-05417-9

• Soft and dispersed interface-rich aqueous systems that promote and guide chemical reactions

  Nature Reviews Chemistry 2, 306–327. doi: 10.1038/s41570-018-0042-6 (2018)

• Core-excited microsecond isomer in 207Pb

  Physical Review C. American Physical Society (APS). 2025 Aug 1. doi: 10.1103/6l8p-cblc